Gene

actmap

ID

ZDB-GENE-061013-199

Name

actin maturation protease

Symbol

actmap Nomenclature History

Previous Names

zgc:153119

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable initiator methionyl aminopeptidase activity. Predicted to be involved in protein processing. Predicted to act upstream of or within proteolysis. Predicted to be located in cytoplasm. Orthologous to human ACTMAP (actin maturation protease).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa14663	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa29064	Allele with one point mutation	Unknown	Splice Site	ENU

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Sequence Targeting Reagents

No data available

Human Disease

Associated With actmap Human Ortholog

No data available

Associated With actmap Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR040043	Actin maturation protease

Domain Details Per Protein

Protein	Additional Resources	Length	Actin maturation protease
UniProtKB:A0A8M9PA75	InterPro	213
UniProtKB:B0V3H4	InterPro	307

Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 18

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	zgc:153119-201 (1) Ensembl	Ensembl		1,375 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	DKEY-233H2	CU138549	ZFIN Curated Data
Encodes	cDNA	MGC:153119	BC124642	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001077275 (1)	1375 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CU138549 (2)	186811 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:B0V3H4 (1)	307 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance

Species	Symbol	Chromosome	Accession #	Evidence
Human	ACTMAP	19	Ensembl:ENSG00000188493 Gene:284325 HGNC:24758 OMIM:620093	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)
Mouse	Actmap	7	Ensembl:ENSMUSG00000078786 Gene:414069 MGI:3041247	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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