Gene

rhot1b

ID

ZDB-GENE-061009-52

Name

ras homolog family member T1

Symbol

rhot1b Nomenclature History

Previous Names

Rhot1a (1)
si:dkeyp-97g3.6

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have GTP binding activity and GTPase activity. Predicted to be involved in several processes, including Rho protein signal transduction; mitochondrion transport along microtubule; and regulation of mitochondrion organization. Localizes to mitochondrion. Is expressed in head. Orthologous to human RHOT1 (ras homolog family member T1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Hollister et al., 2016

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Hollister et al., 2016
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rhot1b Human Ortholog

No data available

Associated With rhot1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR002048	EF-hand domain
Domain	IPR005225	Small GTP-binding domain
Domain	IPR013566	Mitochondrial Rho GTPase 1/3, EF hand associated, type-1
Domain	IPR013567	EF hand associated, type-2
Domain	IPR020860	MIRO domain
Family	IPR001806	Small GTPase
Family	IPR003578	Small GTPase Rho
Family	IPR021181	Mitochondrial Rho GTPase
Family	IPR052266	Mitochondrial Rho GTPase/EF-hand domain-containing protein
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	EF-Hand 1, calcium-binding site	EF hand associated, type-2	EF-hand domain	EF-hand domain pair	MIRO domain	Mitochondrial Rho GTPase	Mitochondrial Rho GTPase 1/3, EF hand associated, type-1	Mitochondrial Rho GTPase/EF-hand domain-containing protein	P-loop containing nucleoside triphosphate hydrolase	Small GTPase	Small GTPase Rho	Small GTP-binding domain
UniProtKB:A0A8M9PZT5 InterPro	626
UniProtKB:B3DI88 InterPro	660
UniProtKB:A0A8M9QFG5 InterPro	480
UniProtKB:A0A8M2BDN6 InterPro	659
UniProtKB:A0A8M9Q658 InterPro	619