Gene
mmp16b
- ID
- ZDB-GENE-061009-22
- Name
- matrix metallopeptidase 16b (membrane-inserted)
- Symbol
- mmp16b Nomenclature History
- Previous Names
-
- si:ch211-261f3.1
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process; extracellular matrix organization; and skeletal system development. Predicted to act upstream of or within proteolysis. Predicted to be located in extracellular matrix and membrane. Predicted to be active in plasma membrane. Orthologous to human MMP16 (matrix metallopeptidase 16).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Quick et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Thyme et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR021158 | Peptidase M10A, cysteine switch, zinc binding site |
| Conserved_site | IPR018486 | Hemopexin, conserved site |
| Domain | IPR000585 | Hemopexin-like domain |
| Domain | IPR001818 | Peptidase M10, metallopeptidase |
| Domain | IPR002477 | Peptidoglycan binding-like |
| Domain | IPR006026 | Peptidase, metallopeptidase |
| Domain | IPR021805 | Peptidase M10A, matrix metallopeptidase, C-terminal |
| Domain | IPR033739 | Peptidase M10A, catalytic domain |
| Family | IPR021190 | Peptidase M10A |
| Homologous_superfamily | IPR024079 | Metallopeptidase, catalytic domain superfamily |
| Homologous_superfamily | IPR036365 | PGBD-like superfamily |
| Homologous_superfamily | IPR036375 | Hemopexin-like domain superfamily |
| Repeat | IPR018487 | Hemopexin-like repeats |
Domain Details Per Protein
| Protein | Length | Hemopexin, conserved site | Hemopexin-like domain | Hemopexin-like domain superfamily | Hemopexin-like repeats | Metallopeptidase, catalytic domain superfamily | Peptidase M10A | Peptidase M10A, catalytic domain | Peptidase M10A, cysteine switch, zinc binding site | Peptidase M10A, matrix metallopeptidase, C-terminal | Peptidase M10, metallopeptidase | Peptidase, metallopeptidase | Peptidoglycan binding-like | PGBD-like superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1R8N4
|
618 | |||||||||||||
|
UniProtKB:A0A8N7TFK6
|
613 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mmp16b-201
(1)
|
Ensembl | 1,785 nt | ||
| mRNA |
mmp16b-202
(1)
|
Ensembl | 3,087 nt |
Interactions and Pathways
No data available
Plasmids
No data available