Gene
fam168b
- ID
- ZDB-GENE-060929-180
- Name
- family with sequence similarity 168 member B
- Symbol
- fam168b Nomenclature History
- Previous Names
-
- fb25h10
- wu:fb25h10
- zgc:153980
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to be located in axon; perinuclear region of cytoplasm; and plasma membrane. Is expressed in brain. Orthologous to human FAM168B (family with sequence similarity 168 member B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Zhang et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Zhang et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| hza8 | Allele with one deletion | Unknown | Unknown | CRISPR |
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| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-fam168b | Zhang et al., 2020 | |
| MO1-fam168b | N/A | Zhang et al., 2020 |
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Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR029247 | FAM168A/MANI |
Domain Details Per Protein
| Protein | Additional Resources | Length | FAM168A/MANI |
|---|---|---|---|
| UniProtKB:A0A0R4IF02 | InterPro | 194 | |
| UniProtKB:Q08BY2 | InterPro | 195 | |
| UniProtKB:A0A8M9PG28 | InterPro | 178 | |
| UniProtKB:A0A8M9P5X8 | InterPro | 179 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fam168b-201
(1)
|
Ensembl | 1,014 nt | ||
| mRNA |
fam168b-202
(1)
|
Ensembl | 1,933 nt | ||
| ncRNA |
fam168b-003
(1)
|
Ensembl | 754 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-189O17 | ZFIN Curated Data | |
| Encodes | EST | fb25h10 | ||
| Encodes | cDNA | MGC:153980 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001076569 (1) | 1921 nt | ||
| Genomic | GenBank:CR548632 (1) | 178393 nt | ||
| Polypeptide | UniProtKB:Q08BY2 (1) | 195 aa |
- Zhang, T., Guan, P., Liu, W., Zhao, G., Fang, Y., Fu, H., Gui, J.F., Li, G., Liu, J.X. (2020) Copper Stress Induces Zebrafish Central Neural System Myelin Defects via WNT/NOTCH-hoxb5b Signaling and pou3f1/fam168a/fam168b DNA Methylation. Biochimica et biophysica acta. Gene regulatory mechanisms. 1863(10):194612
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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