ZFIN ID: ZDB-GENE-060929-164
Gene Name: RUNX1 partner transcriptional co-repressor 1
Gene Symbol: runx1t1    Nomenclature History

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Previous Names: wu:fi14b07, zgc:154044

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in negative regulation of apoptotic process; protein autophosphorylation; and regulation of mitotic cell cycle. Predicted to localize to cytoplasm. Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1).
Genome Resources: Alliance (1),  Gene:767809 (1),  Ensembl(GRCz11):ENSDARG00000003680 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa29233 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH runx1t1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH runx1t1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of transcription, DNA-templated (more)
    Cellular Component cytoplasm (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript runx1t1-205 (1)    Ensembl 745
    mRNA runx1t1-202 (1)    Ensembl 1305
    runx1t1-203 (1)    Ensembl 5244
    runx1t1-204 (1)    Ensembl 632
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM runx1t1 No data available
    MARKER RELATIONSHIPS
    runx1t1 Contained in: [BAC] CH211-232J17 (1), DKEYP-79C4 (1)
    runx1t1 Encodes: [EST] fi14b07, fj53h11
    [cDNA] MGC:154044 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001076776 (1) 1767 nt
    Genomic GenBank:CR759910 (1) 217814 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IXV4 (1) 591 aa
    Sequence Information (all 29)
    ORTHOLOGY for runx1t1 ( Chr: 19 )
    CITATIONS (24)