Gene

igf2bp1

ID

ZDB-GENE-060929-1258

Name

insulin-like growth factor 2 mRNA binding protein 1

Symbol

igf2bp1 Nomenclature History

Previous Names

fb96d05
wu:fb18f03
wu:fb96d05
wu:fi72a06
zgc:152963

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have mRNA 3'-UTR binding activity. Involved in neural retina development. Predicted to localize to CRD-mediated mRNA stability complex. Is expressed in diencephalic white matter and head. Orthologous to human IGF2BP1 (insulin like growth factor 2 mRNA binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With igf2bp1 Human Ortholog

No data available

Associated With igf2bp1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR004087	K Homology domain
Domain	IPR004088	K Homology domain, type 1
Domain	IPR034837	IGF2BP1, RNA recognition motif 1
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily
Homologous_superfamily	IPR036612	K Homology domain, type 1 superfamily

Domain Details Per Protein

Protein	Length	IGF2BP1, RNA recognition motif 1	K Homology domain	K Homology domain, type 1	K Homology domain, type 1 superfamily	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA recognition motif domain
UniProtKB:A0A0B4J1A6 InterPro	598
UniProtKB:Q08CK7 InterPro	598

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	igf2bp1-201 (1) Ensembl	Ensembl	8,478 nt	Select Tool
mRNA	igf2bp1-203 (1) Ensembl	Ensembl	747 nt	Select Tool
mRNA	igf2bp1-204 (1) Ensembl	Ensembl	1,912 nt	Select Tool ZFIN BLAST
ncRNA	igf2bp1-003 (1) Ensembl	Ensembl	666 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations