Gene

rnf220a

ID

ZDB-GENE-060929-1006

Name

ring finger protein 220a

Symbol

rnf220a Nomenclature History

Previous Names

zgc:153254

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have metal ion binding activity and ubiquitin-protein transferase activity. Orthologous to human RNF220 (ring finger protein 220).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Ma et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rnf220a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hypomyelinating leukodystrophy 23	Alliance	Leukodystrophy, hypomyelinating, 23, with ataxia, deafness, liver dysfunction, and dilated cardiomyopathy	619688

Associated With rnf220a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR031824	E3 ubiquitin-protein ligase RNF220, middle domain
Domain	IPR040178	E3 ubiquitin-protein ligase RNF220, RING finger
Family	IPR052443	E3 ubiquitin-protein ligase RNF220-like
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type

Domain Details Per Protein

Protein	Length	E3 ubiquitin-protein ligase RNF220-like	E3 ubiquitin-protein ligase RNF220, middle domain	E3 ubiquitin-protein ligase RNF220, RING finger	Zinc finger, RING/FYVE/PHD-type	Zinc finger, RING-type
UniProtKB:A0A8M9QNG6 InterPro	669
UniProtKB:A0A8M9PY31 InterPro	333
UniProtKB:A0A8M9Q9U5 InterPro	634
UniProtKB:A0A8M9PY03 InterPro	638
UniProtKB:A0A8M9QJR7 InterPro	660
UniProtKB:A0A8M9QJS5 InterPro	399
UniProtKB:A0A8M9QFI1 InterPro	577
UniProtKB:A0A8M9QFJ4 InterPro	307
UniProtKB:A0A8M9Q9V4 InterPro	364
UniProtKB:Q08CD0 InterPro	307
UniProtKB:A0A8M9PXZ7 InterPro	695
UniProtKB:A0A8M9QFH8 InterPro	615
UniProtKB:A0A8M9PY10 InterPro	603
UniProtKB:A0A8M9Q9V8 InterPro	338

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	rnf220a-205 (1) Ensembl	Ensembl	855 nt	Select Tool
mRNA	rnf220a-201 (1) Ensembl	Ensembl	1,614 nt	Select Tool
mRNA	rnf220a-202 (1) Ensembl	Ensembl	1,734 nt	Select Tool
mRNA	rnf220a-203 (1) Ensembl	Ensembl	762 nt	Select Tool
mRNA	rnf220a-204 (1) Ensembl	Ensembl	694 nt	Select Tool
mRNA	rnf220a-206 (1) Ensembl	Ensembl	604 nt	Select Tool
mRNA	rnf220a-207 (1) Ensembl	Ensembl	1,339 nt	Select Tool ZFIN BLAST
mRNA	rnf220a-208 (1) Ensembl	Ensembl	2,707 nt	Select Tool ZFIN BLAST
mRNA	rnf220a-209 (1) Ensembl	Ensembl	5,466 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations