ZFIN ID: ZDB-GENE-060825-251
Gene Name: GTP binding protein overexpressed in skeletal muscle
Gene Symbol: gem    Nomenclature History

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Previous Name: zgc:153003

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Exhibits calcium channel regulator activity. Predicted to be involved in negative regulation of high voltage-gated calcium channel activity and signal transduction. Predicted to localize to plasma membrane. Orthologous to human GEM (GTP binding protein overexpressed in skeletal muscle).
Genome Resources: Alliance (1),  Gene:560566 (1),  Ensembl(GRCz11):ENSDARG00000029112 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16656 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gem HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gem VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of high voltage-gated calcium channel activity (more)
    Cellular Component membrane (more)
    Molecular Function calcium channel regulator activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gem-201 (1)    Ensembl 1538
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gem No data available
    MARKER RELATIONSHIPS
    gem Contained in: [BAC] CH211-79L20
    gem Encodes: [cDNA] MGC:153003 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045849 (1) 1557 nt
    Genomic GenBank:BX511010 (1) 156317 nt
    Select Tool
    Polypeptide UniProtKB:Q0P4E7 (1) 291 aa
    Sequence Information (all 10)
    ORTHOLOGY for gem ( Chr: 16 )
    CITATIONS (19)