Gene

plk2a

ID

ZDB-GENE-060810-71

Name

polo-like kinase 2a (Drosophila)

Symbol

plk2a Nomenclature History

Previous Names

im:7157189

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mitotic spindle organization. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in centriole and dendrite. Predicted to be active in several cellular components, including kinetochore; microtubule cytoskeleton; and nucleus. Is expressed in blood vessel; brain; nervous system; and vasculature. Orthologous to human PLK2 (polo like kinase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7157189 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With plk2a Human Ortholog

No data available

Associated With plk2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR000959	POLO box domain
Domain	IPR033695	Second polo-box domain
Domain	IPR033701	First polo-box domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR036947	POLO box domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	First polo-box domain	POLO box domain	POLO box domain superfamily	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Second polo-box domain	Serine/threonine-protein kinase, active site
UniProtKB:A0A8M1RNL4	InterPro	678

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	plk2-201 (1) Ensembl	Ensembl		2,013 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations