Gene

eif4ba

ID

ZDB-GENE-060629-1

Name

eukaryotic translation initiation factor 4Ba

Symbol

eif4ba Nomenclature History

Previous Names

eif4b (1)

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable RNA strand annealing activity; RNA strand-exchange activity; and ribosomal small subunit binding activity. Predicted to be involved in eukaryotic translation initiation factor 4F complex assembly and formation of translation preinitiation complex. Predicted to act upstream of or within translational initiation. Orthologous to human EIF4B (eukaryotic translation initiation factor 4B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Chen et al., 2018

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eif4ba Human Ortholog

No data available

Associated With eif4ba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR033107	Eukaryotic translation initiation factor 4B, RNA recognition motif
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Eukaryotic translation initiation factor 4B, RNA recognition motif	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA recognition motif domain
UniProtKB:F1QAA4 InterPro	529
UniProtKB:A0A0R4IMF6 InterPro	616
UniProtKB:A0A8M2B8R4 InterPro	578

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	eif4ba-201 (1) Ensembl	Ensembl	2,492 nt	Select Tool ZFIN BLAST
mRNA	eif4ba-202 (1) Ensembl	Ensembl	1,100 nt	Select Tool ZFIN BLAST
mRNA	eif4ba-203 (1) Ensembl	Ensembl	406 nt	Select Tool ZFIN BLAST
mRNA	eif4ba-204 (1) Ensembl	Ensembl	6,370 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations