Gene
dgkaa
- ID
- ZDB-GENE-060616-305
- Name
- diacylglycerol kinase, alpha a
- Symbol
- dgkaa Nomenclature History
- Previous Names
-
- zgc:136759
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable ATP-dependent diacylglycerol kinase activity. Predicted to be involved in diacylglycerol metabolic process; intracellular signal transduction; and phosphatidic acid biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Orthologous to human DGKA (diacylglycerol kinase alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Domain | IPR000756 | Diacylglycerol kinase, accessory domain |
| Domain | IPR001206 | Diacylglycerol kinase, catalytic domain |
| Domain | IPR002048 | EF-hand domain |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR029477 | Diacylglycerol kinase type I, N-terminal |
| Domain | IPR047469 | Diacylglycerol kinase alpha, second protein kinase C conserved region 1 |
| Family | IPR037607 | Diacylglycerol kinase |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR016064 | NAD kinase/diacylglycerol kinase-like domain superfamily |
| Homologous_superfamily | IPR017438 | Inorganic polyphosphate/ATP-NAD kinase, N-terminal |
| Homologous_superfamily | IPR038199 | DGK type I, N-terminal domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C1-like domain superfamily | DGK type I, N-terminal domain superfamily | Diacylglycerol kinase | Diacylglycerol kinase, accessory domain | Diacylglycerol kinase alpha, second protein kinase C conserved region 1 | Diacylglycerol kinase, catalytic domain | Diacylglycerol kinase type I, N-terminal | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | Inorganic polyphosphate/ATP-NAD kinase, N-terminal | NAD kinase/diacylglycerol kinase-like domain superfamily | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8Q6S0 | InterPro | 766 | |||||||||||||
| UniProtKB:Q1ECW5 | InterPro | 727 |
Interactions and Pathways
No data available
Plasmids
No data available