Gene
card9
- ID
- ZDB-GENE-060531-94
- Name
- caspase recruitment domain family, member 9
- Symbol
- card9 Nomenclature History
- Previous Names
-
- si:dkey-1o2.6
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have CARD domain binding activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis. Is expressed in brain; gill; liver; pleuroperitoneal region; and unfertilized egg. Orthologous to human CARD9 (caspase recruitment domain family member 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| chronic mucocutaneous candidiasis | Alliance | Immunodeficiency 103, susceptibility to fungal infection | 212050 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CARD9, CARD domain | CARD domain | Death-like domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M3AZX7
|
521 | |||
|
UniProtKB:A0A8M3B9W3
|
568 | |||
|
UniProtKB:A0A8M3B2T4
|
556 | |||
|
UniProtKB:A0A8M2BD15
|
557 | |||
|
UniProtKB:A2CE85
|
534 | |||
|
UniProtKB:A0A8M3ASS5
|
566 | |||
|
UniProtKB:A0A8M3ASN6
|
577 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available