Gene
npr3
- ID
- ZDB-GENE-060531-91
- Name
- natriuretic peptide receptor 3
- Symbol
- npr3 Nomenclature History
- Previous Names
-
- im:7138418
- si:dkey-199l1.2 (1)
- zgc:158440
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Involved in cardiac muscle cell proliferation. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hypertension. Is expressed in several structures, including heart; hypochord; nervous system; neural tube; and renal system. Orthologous to human NPR3 (natriuretic peptide receptor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138418 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Becker et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Boudin-Mortier syndrome | 619543 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adenylyl cyclase class-4/guanylyl cyclase | Atrial Natriuretic Peptide Clearance Receptor | Periplasmic binding protein-like I | Receptor, ligand binding region |
|---|---|---|---|---|---|
|
UniProtKB:A2RUY7
|
472 | ||||
|
UniProtKB:A0A2R8RSJ1
|
503 |
Interactions and Pathways
No data available
Plasmids
No data available