Gene

stim1b

ID

ZDB-GENE-060531-4

Name

stromal interaction molecule 1b

Symbol

stim1b Nomenclature History

Previous Names

stim1
si:ch211-112l17.2

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have calcium channel regulator activity and calcium ion binding activity. Predicted to be involved in activation of store-operated calcium channel activity; cellular calcium ion homeostasis; and store-operated calcium entry. Predicted to localize to endoplasmic reticulum and plasma membrane. Human ortholog(s) of this gene implicated in Stormorken syndrome; primary immunodeficiency disease; and tubular aggregate myopathy. Orthologous to human STIM1 (stromal interaction molecule 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With stim1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
immunodeficiency 10	Alliance	Immunodeficiency 10	612783
Stormorken syndrome	Alliance	Stormorken syndrome	185070
tubular aggregate myopathy 1	Alliance	Myopathy, tubular aggregate, 1	160565

Associated With stim1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001660	Sterile alpha motif domain
Domain	IPR032393	Stromal interaction molecule, Orai1-activating region
Family	IPR037608	Stromal interaction molecule
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily