Gene
stim1b
- ID
- ZDB-GENE-060531-4
- Name
- stromal interaction molecule 1b
- Symbol
- stim1b Nomenclature History
- Previous Names
-
- stim1
- si:ch211-112l17.2
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable calcium channel regulator activity and calcium ion binding activity. Predicted to be involved in intracellular calcium ion homeostasis and store-operated calcium entry. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum and plasma membrane. Is expressed in several structures, including brain; head; liver; pleuroperitoneal region; and skeletal muscle. Human ortholog(s) of this gene implicated in Stormorken syndrome; gastrointestinal system cancer (multiple); immunodeficiency 10; lung cancer; and tubular aggregate myopathy 1. Orthologous to human STIM1 (stromal interaction molecule 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 10 | Alliance | Immunodeficiency 10 | 612783 |
| Stormorken syndrome | Alliance | Stormorken syndrome | 185070 |
| tubular aggregate myopathy 1 | Alliance | Myopathy, tubular aggregate, 1 | 160565 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily | Stromal interaction molecule | Stromal interaction molecule, Orai1-activating region |
|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IAT9 | InterPro | 668 | ||||
| UniProtKB:F1R6G6 | InterPro | 641 | ||||
| UniProtKB:A0A8M1P2M0 | InterPro | 642 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stim1b-201
(1)
|
Ensembl | 2,120 nt | ||
| mRNA |
stim1b-202
(1)
|
Ensembl | 2,575 nt |
Interactions and Pathways
No data available
Plasmids
No data available