Gene

f2r

ID
ZDB-GENE-060526-30
Name
coagulation factor II (thrombin) receptor
Symbol
f2r Nomenclature History
Previous Names
  • PAR1-5A (1)
  • si:ch211-130m23.4
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Enables thrombin-activated receptor activity. Acts upstream of or within circulatory system development; endothelial to hematopoietic transition; and negative regulation of hematopoietic stem cell differentiation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; digestive system; hematopoietic system; mesoderm; and pleuroperitoneal region. Orthologous to human F2R (coagulation factor II thrombin receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With f2r Human Ortholog
No data available
Associated With f2r Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000935 Thrombin receptor
Family IPR003912 Protease-activated receptor
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Protease-activated receptor Thrombin receptor
UniProtKB:A2BIP6 413
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations