ZFIN is now using GRCz12tu for Genomic Data
Gene
f2r
- ID
- ZDB-GENE-060526-30
- Name
- coagulation factor II (thrombin) receptor
- Symbol
- f2r Nomenclature History
- Previous Names
-
- PAR1-5A (1)
- si:ch211-130m23.4
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables thrombin-activated receptor activity. Acts upstream of or within circulatory system development; endothelial to hematopoietic transition; and negative regulation of hematopoietic stem cell differentiation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including cardiovascular system; digestive system; hematopoietic system; mesoderm; and pleuroperitoneal region. Orthologous to human F2R (coagulation factor II thrombin receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Protease-activated receptor | Thrombin receptor |
|---|---|---|---|---|---|---|
| UniProtKB:A2BIP6 | InterPro | 413 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers