Gene

arhgef15a

ID
ZDB-GENE-060526-292
Name
Rho guanine nucleotide exchange factor (GEF) 15
Symbol
arhgef15a Nomenclature History
Previous Names
  • arhgef15
  • si:dkey-2j6.3
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of actin cytoskeleton organization. Orthologous to human ARHGEF15 (Rho guanine nucleotide exchange factor 15).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa40581Allele with one point mutationUnknownSplice SiteENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
1 - 1 of 1
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Sequence Targeting Reagents
No data available
Human Disease
Associated With arhgef15a Human Ortholog
No data available
Associated With arhgef15a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR047270 Ephexin-like, PH domain
Family IPR047271 Ephexin-like
Homologous_superfamily IPR011993 PH-like domain superfamily
1 - 5 of 7 Show all
Domain Details Per Protein
Protein Additional Resources Length Dbl homology (DH) domain superfamily Ephexin-like Ephexin-like, PH domain PH-like domain superfamily Pleckstrin homology domain SH3 domain SH3-like domain superfamily
UniProtKB:A0A8M6Z762 InterPro 924
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA arhgef15-201 (1)
Ensembl
Ensembl 7,649 nt
ZFIN BLAST
mRNA arhgef15-202 (1)
Ensembl
Ensembl 1,549 nt
ZFIN BLAST
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-2J6ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_017356341 (1)
ZFIN BLASTNCBI BLASTMegaBLASTEnsemblUCSC BLAT
GenomicGenBank:CR450749 (1)142889 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A8M6Z762 (1)924 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanARHGEF1517
Amino acid sequence comparison (1)
Phylogenetic tree (1)
Conserved genome location (synteny) (1)
MouseArhgef1511
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Phylogenetic tree (1)
Citations
TSV
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