Gene
rangrf
- ID
- ZDB-GENE-060526-143
- Name
- RAN guanine nucleotide release factor
- Symbol
- rangrf Nomenclature History
- Previous Names
-
- Mog1 (1)
- si:ch211-268m12.6
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including guanyl-nucleotide exchange factor activity; small GTPase binding activity; and transmembrane transporter binding activity. Acts upstream of or within several processes, including heart contraction; heart development; and regulation of heart looping. Predicted to be located in perinuclear region of cytoplasm and plasma membrane. Predicted to be active in nucleus. Is expressed in blastomere; brain; eye; fin; and heart. Orthologous to human RANGRF (RAN guanine nucleotide release factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-rangrf | N/A | Zhou et al., 2016 |
| MO2-rangrf | N/A | Zhou et al., 2016 |
| TALEN1-rangrf | Gou et al., 2020 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Mog1/PsbP, alpha/beta/alpha sandwich | Ran-interacting Mog1 protein |
|---|---|---|---|---|
| UniProtKB:A3KPP3 | InterPro | 183 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rangrf-201
(1)
|
Ensembl | 1,066 nt | ||
| mRNA |
rangrf-202
(1)
|
Ensembl | 1,244 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-268M12 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-9F14 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:171693 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001099995 (1) | 552 nt | ||
| Genomic | GenBank:CR749165 (2) | 61537 nt | ||
| Polypeptide | UniProtKB:A3KPP3 (1) | 183 aa |