Gene

npepps

ID

ZDB-GENE-060524-3

Name

aminopeptidase puromycin sensitive

Symbol

npepps Nomenclature History

Previous Names

psa
fb68d07
sb:cb848
sb:eu910
wu:fb68d07

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Enables aminopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be active in cytoplasm; extracellular space; and membrane. Is expressed in nervous system; pectoral fin musculature; and proliferative region. Orthologous to human NPEPPS (aminopeptidase puromycin sensitive).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb848 (6 images)
eu910 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With npepps Human Ortholog

No data available

Associated With npepps Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR014782	Peptidase M1, membrane alanine aminopeptidase
Domain	IPR024571	ERAP1-like C-terminal domain
Domain	IPR045357	Aminopeptidase N-like , N-terminal domain
Family	IPR001930	Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
Family	IPR034016	Aminopeptidase N-type
Family	IPR050344	Peptidase M1 family aminopeptidases
Homologous_superfamily	IPR027268	Peptidase M4/M1, CTD superfamily
Homologous_superfamily	IPR042097	Aminopeptidase N-like , N-terminal domain superfamliy