Gene

npepps

ID
ZDB-GENE-060524-3
Name
aminopeptidase puromycin sensitive
Symbol
npepps Nomenclature History
Previous Names
  • psa
  • fb68d07
  • sb:cb848
  • sb:eu910
  • wu:fb68d07
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Enables aminopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be active in cytoplasm; extracellular space; and membrane. Is expressed in nervous system; pectoral fin musculature; and proliferative region. Orthologous to human NPEPPS (aminopeptidase puromycin sensitive).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa35043Allele with one point mutationUnknownSplice SiteENU
1 - 1 of 1
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-npepps
    Keatinge et al., 2021
    1 - 1 of 1
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    Human Disease
    Associated With npepps Human Ortholog
    No data available
    Associated With npepps Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Domain IPR014782 Peptidase M1, membrane alanine aminopeptidase
    Domain IPR024571 ERAP1-like C-terminal domain
    Domain IPR045357 Aminopeptidase N-like , N-terminal domain
    Family IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
    Family IPR034016 Aminopeptidase N-type
    1 - 5 of 8 Show all
    Domain Details Per Protein
    Protein Additional Resources Length Aminopeptidase N-like , N-terminal domain Aminopeptidase N-like , N-terminal domain superfamliy Aminopeptidase N-type ERAP1-like C-terminal domain Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase Peptidase M1 family aminopeptidases Peptidase M1, membrane alanine aminopeptidase Peptidase M4/M1, CTD superfamily
    UniProtKB:A0A8M1NSE3 InterPro 872
    1 - 1 of 1
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 11
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA npepps-201 (1) Ensembl 4,426 nt
    1 - 1 of 1
    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH211-156L18ZFIN Curated Data
    EncodesESTcb848Thisse et al., 2001
    EncodesESTeu910Thisse et al., 2005
    Has ArtifactESTfb68d07
    1 - 4 of 4
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanNPEPPS17
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    MouseNpepps11
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    Citations