Gene

tax1bp1a

ID

ZDB-GENE-060503-587

Name

Tax1 (human T-cell leukemia virus type I) binding protein 1a

Symbol

tax1bp1a Nomenclature History

Previous Names

si:ch211-204j16.2 (1)

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to enable metal ion binding activity. Predicted to act upstream of or within apoptotic process. Orthologous to human TAX1BP1 (Tax1 binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Ahn et al., 2008

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa36815	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)
sa36816	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)
sa36817	Allele with one point mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)
sa36818	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With tax1bp1a Human Ortholog

No data available

Associated With tax1bp1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR012852	Calcium binding and coiled-coil domain-like
Domain	IPR041611	SKICH domain
Domain	IPR041641	CALCOCO1/2, zinc finger UBZ1-type
Family	IPR051002	Ubiquitin-binding and autophagy-associated domain-containing protein

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Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A2C9F1R8	InterPro	796
UniProtKB:Q1LWB0	InterPro	781
UniProtKB:A0AB32TEF4	InterPro	733

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Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 19

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tax1bp1a-201 (1) Ensembl	Ensembl	5,200 nt	Select Tool ZFIN BLAST
mRNA	tax1bp1a-202 (1) Ensembl	Ensembl	537 nt	Select Tool ZFIN BLAST
mRNA	tax1bp1a-203 (1) Ensembl	Ensembl	3,012 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	CH211-204J16	BX601646	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001346178 (1)		Select Tool ZFIN BLAST NCBI BLAST MegaBLAST Ensembl UCSC BLAT
Genomic	GenBank:BX601646 (1)	163533 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A2C9F1R8 (1)	796 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	TAX1BP1	7	Ensembl:ENSG00000106052 Gene:8887 HGNC:11575 OMIM:605326	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)
Mouse	Tax1bp1	6	Ensembl:ENSMUSG00000004535 Gene:52440 MGI:1289308	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)

Citations

Include unpublished citations

Ahn, D., and Ho, R.K. (2008) Tri-phasic expression of posterior Hox genes during development of pectoral fins in zebrafish: Implications for the evolution of vertebrate paired appendages. Developmental Biology. 322(1):220-233

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