Gene

elp2

ID
ZDB-GENE-060503-525
Name
elongator acetyltransferase complex subunit 2
Symbol
elp2 Nomenclature History
Previous Names
  • si:dkey-190l1.1
  • zgc:153559
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to be involved in tRNA wobble uridine modification. Predicted to localize to elongator holoenzyme complex and transcription elongation factor complex. Is expressed in female organism. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human ELP2 (elongator acetyltransferase complex subunit 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Newman et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With elp2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mental retardation, autosomal recessive 58 617270
Associated With elp2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017986 WD40-repeat-containing domain
Family IPR037289 Elongator complex protein 2
Homologous_superfamily IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily Elongator complex protein 2 WD40 repeat WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q05AM5 821
UniProtKB:A0A286Y893 821
UniProtKB:B5DDH6 821
UniProtKB:Z4YI78 836
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations