Gene

slc17a8

ID
ZDB-GENE-060503-416
Name
solute carrier family 17 member 8
Symbol
slc17a8 Nomenclature History
Previous Names
  • asteroid (1)
  • si:ch211-264e16.4
  • vesicular glutamate transporter 3 (1)
  • vglut3 (2)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have L-glutamate transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Involved in equilibrioception; regulation of synapse structure or activity; and vestibular reflex. Predicted to localize to excitatory synapse and integral component of synaptic vesicle membrane. Is expressed in hair cell; hair cell anterior macula; inner ear; neuromast; and neuromast hair cell. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Orthologous to human SLC17A8 (solute carrier family 17 member 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc17a8 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant nonsyndromic deafness 25 Alliance Deafness, autosomal dominant 25 605583
Associated With slc17a8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR020846 Major facilitator superfamily domain
Family IPR011701 Major facilitator superfamily
Homologous_superfamily IPR036259 MFS transporter superfamily
Domain Details Per Protein
Protein Length Major facilitator superfamily Major facilitator superfamily domain MFS transporter superfamily
UniProtKB:Q1L8X9 590
UniProtKB:B5AU16 590
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-slc17a8 polyclonal Rabbit
  • IHC
8
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations