Gene
gale
- ID
- ZDB-GENE-060421-6479
- Name
- UDP-galactose-4-epimerase
- Symbol
- gale Nomenclature History
- Previous Names
-
- fb05f01
- im:7147391
- wu:fb05f01
- zgc:136578
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable UDP-glucose 4-epimerase activity. Predicted to be involved in galactose catabolic process via UDP-galactose. Predicted to act upstream of or within galactose metabolic process. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in galactose epimerase deficiency and thrombocytopenia. Orthologous to human GALE (UDP-galactose-4-epimerase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7147391 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| galactose epimerase deficiency | Alliance | Galactose epimerase deficiency | 230350 |
| Thrombocytopenia 13, syndromic | 620776 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NAD(P)-binding domain | NAD(P)-binding domain superfamily | UDP-glucose 4-epimerase |
|---|---|---|---|---|
|
UniProtKB:F1Q5H4
|
350 | |||
|
UniProtKB:Q1RM15
|
349 |
Interactions and Pathways
No data available
Plasmids
No data available