Gene

mmp30

ID

ZDB-GENE-060421-5765

Name

matrix metallopeptidase 30

Symbol

mmp30 Nomenclature History

Previous Names

MMPLf (1)
zgc:136396

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; artery disease (multiple); carcinoma (multiple); coronary aneurysm; and end stage renal disease. Orthologous to human MMP12 (matrix metallopeptidase 12); MMP26 (matrix metallopeptidase 26); and MMP3 (matrix metallopeptidase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mmp30 Human Ortholog

No data available

Associated With mmp30 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000585	Hemopexin-like domain
Domain	IPR001818	Peptidase M10, metallopeptidase
Domain	IPR002477	Peptidoglycan binding-like
Domain	IPR006026	Peptidase, metallopeptidase
Domain	IPR033739	Peptidase M10A, catalytic domain
Family	IPR021190	Peptidase M10A
Homologous_superfamily	IPR024079	Metallopeptidase, catalytic domain superfamily
Homologous_superfamily	IPR036365	PGBD-like superfamily
Homologous_superfamily	IPR036375	Hemopexin-like domain superfamily
Repeat	IPR018487	Hemopexin-like repeats

Domain Details Per Protein

Protein	Additional Resources	Length	Hemopexin-like domain	Hemopexin-like domain superfamily	Hemopexin-like repeats	Metallopeptidase, catalytic domain superfamily	Peptidase M10A	Peptidase M10A, catalytic domain	Peptidase M10, metallopeptidase	Peptidase, metallopeptidase	Peptidoglycan binding-like	PGBD-like superfamily
UniProtKB:Q1RM69	InterPro	475

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	mmp30-201 (1) Ensembl	Ensembl		2,637 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations