Gene

baiap2a

ID

ZDB-GENE-060421-2756

Name

BAR/IMD domain containing adaptor protein 2a

Symbol

baiap2a Nomenclature History

Previous Names

wu:fk29g02
zgc:136827

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have cytoskeletal adaptor activity. Predicted to be involved in actin filament organization and positive regulation of cytoskeleton organization. Predicted to localize to cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and autism spectrum disorder. Orthologous to human BAIAP2 (BAR/IMD domain containing adaptor protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With baiap2a Human Ortholog

No data available

Associated With baiap2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001452	SH3 domain
Domain	IPR013606	IMD/I-BAR domain
Domain	IPR030128	I-BAR domain containing protein IRSp53, Inverse-Bin/Amphiphysin/Rvs domain
Domain	IPR035594	IRSp53, SH3 domain
Family	IPR027681	I-BAR domain containing protein IRSp53/IRTKS/Pinkbar
Homologous_superfamily	IPR027267	AH/BAR domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Length	AH/BAR domain superfamily	I-BAR domain containing protein IRSp53, Inverse-Bin/Amphiphysin/Rvs domain	I-BAR domain containing protein IRSp53/IRTKS/Pinkbar	IMD/I-BAR domain	IRSp53, SH3 domain	SH3 domain	SH3-like domain superfamily
UniProtKB:A0A8M3AQY0 InterPro	485
UniProtKB:A0A8M9PQ60 InterPro	536
UniProtKB:Q1RLU7 InterPro	506
UniProtKB:A0A8M2BAV5 InterPro	549
UniProtKB:A0A8M3B8K0 InterPro	465