Gene
sall4
- ID
- ZDB-GENE-060328-2
- Name
- spalt-like transcription factor 4
- Symbol
- sall4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Enables chromatin binding activity. Acts upstream of or within embryonic pectoral fin morphogenesis and positive regulation of fibroblast growth factor receptor signaling pathway. Predicted to be active in nucleus. Is expressed in several structures, including brain; fin bud; mesoderm; neural plate; and neural tube. Human ortholog(s) of this gene implicated in Duane retraction syndrome; Duane-radial ray syndrome; Holt-Oram syndrome; IVIC syndrome; and ventricular septal defect. Orthologous to human SALL4 (spalt like transcription factor 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 27 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb372 (18 images)
- cb614 (19 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Duane-radial ray syndrome | Alliance | Duane-radial ray syndrome | 607323 |
| IVIC syndrome | Alliance | ?IVIC syndrome | 147750 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Sal C2H2-type zinc-finger | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
|
UniProtKB:A0MWC1
|
1091 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available