Gene

sall4

ID
ZDB-GENE-060328-2
Name
spalt-like transcription factor 4
Symbol
sall4 Nomenclature History
Previous Names
  • cb372 (1)
  • cb614 (1)
  • ik:tdsubc_2c1
  • sb:cb372
  • sb:cb614
  • wu:fa01g03
  • xx:tdsubc_2c1
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Exhibits chromatin binding activity. Involved in embryonic pectoral fin morphogenesis and positive regulation of fibroblast growth factor receptor signaling pathway. Predicted to localize to nucleus. Is expressed in several structures, including fin bud; mesoderm; nervous system; neural plate; and neural tube. Human ortholog(s) of this gene implicated in Duane retraction syndrome; Duane-radial ray syndrome; Holt-Oram syndrome; IVIC syndrome; and ventricular septal defect. Orthologous to human SALL4 (spalt like transcription factor 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
25 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sall4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Duane-radial ray syndrome Alliance Duane-radial ray syndrome 607323
IVIC syndrome Alliance IVIC syndrome 147750
Associated With sall4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:A0MWC1 1091
UniProtKB:F1QDF2 1091
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations