ZFIN is now using GRCz12tu for Genomic Data
Gene
arhgef7a
- ID
- ZDB-GENE-060322-11
- Name
- Rho guanine nucleotide exchange factor (GEF) 7a
- Symbol
- arhgef7a Nomenclature History
- Previous Names
-
- fc28d09
- wu:fc28d09
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in lamellipodium assembly. Predicted to be active in cytoplasm and lamellipodium. Orthologous to human ARHGEF7 (Rho guanine nucleotide exchange factor 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144067 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR000219 | Dbl homology domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001715 | Calponin homology domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR032409 | Rho guanine nucleotide exchange factor 6/7, coiled-coil domain |
| Domain | IPR035788 | Rho guanine nucleotide exchange factor 6, SH3 domain |
| Domain | IPR046376 | RhoGEF 6/7, PH domain |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Calponin homology domain | CH domain superfamily | Dbl homology (DH) domain superfamily | Dbl homology domain | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | PH-like domain superfamily | Pleckstrin homology domain | RhoGEF 6/7, PH domain | Rho guanine nucleotide exchange factor 6/7, coiled-coil domain | Rho guanine nucleotide exchange factor 6, SH3 domain | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:B0S771 | InterPro | 858 | ||||||||||||
| UniProtKB:A0A8M9QJM4 | InterPro | 702 | ||||||||||||
| UniProtKB:A0A2R8Q515 | InterPro | 859 | ||||||||||||
| UniProtKB:A0A8M6Z2J5 | InterPro | 782 | ||||||||||||
| UniProtKB:A0A8M2BF23 | InterPro | 807 | ||||||||||||
| UniProtKB:A0A8M2BF17 | InterPro | 777 | ||||||||||||
| UniProtKB:A0A8M9Q4K4 | InterPro | 864 | ||||||||||||
| UniProtKB:A0A8M2BEZ3 | InterPro | 802 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arhgef7a-202
(1)
|
Ensembl | 3,312 nt | ||
| mRNA |
arhgef7a-204
(1)
|
Ensembl | 6,971 nt | ||
| ncRNA |
arhgef7a-002
(1)
|
Ensembl | 2,491 nt | ||
| ncRNA |
arhgef7a-003
(1)
|
Ensembl | 556 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers