Gene

arhgef7a

ID
ZDB-GENE-060322-11
Name
Rho guanine nucleotide exchange factor (GEF) 7a
Symbol
arhgef7a Nomenclature History
Previous Names
  • fc28d09
  • wu:fc28d09
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction. Predicted to localize to lamellipodium. Orthologous to human ARHGEF7 (Rho guanine nucleotide exchange factor 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arhgef7a Human Ortholog
No data available
Associated With arhgef7a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved site
Domain IPR000219 Dbl homology (DH) domain
Domain IPR001452 SH3 domain
Domain IPR001715 Calponin homology domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR032409 Rho guanine nucleotide exchange factor 6/7, coiled-coil domain
Domain IPR035788 Rho guanine nucleotide exchange factor 6, SH3 domain
Domain IPR046376 RhoGEF 6/7, PH domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036872 CH domain superfamily
Domain Details Per Protein
Protein Length Calponin homology domain CH domain superfamily Dbl homology (DH) domain Dbl homology (DH) domain superfamily Guanine-nucleotide dissociation stimulator, CDC24, conserved site PH-like domain superfamily Pleckstrin homology domain RhoGEF 6/7, PH domain Rho guanine nucleotide exchange factor 6/7, coiled-coil domain Rho guanine nucleotide exchange factor 6, SH3 domain SH3 domain SH3-like domain superfamily
UniProtKB:B0S771 858
UniProtKB:A0A8M9QJM4 702
UniProtKB:A0A2R8Q515 859
UniProtKB:A0A8M6Z2J5 782
UniProtKB:A0A8M2BF23 807
UniProtKB:A0A8M2BF17 777
UniProtKB:A0A8M9Q4K4 864
UniProtKB:A0A8M2BEZ3 802
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA arhgef7a-202 (1) Ensembl 3,312 nt
mRNA arhgef7a-204 (1) Ensembl 6,971 nt
ncRNA arhgef7a-002 (1) Ensembl 2,491 nt
ncRNA arhgef7a-003 (1) Ensembl 556 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations