ZFIN is now using GRCz12tu for Genomic Data
Gene
lipt2
- ID
- ZDB-GENE-060312-18
- Name
- lipoyl(octanoyl) transferase 2
- Symbol
- lipt2 Nomenclature History
- Previous Names
-
- zgc:136925
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable lipoyl(octanoyl) transferase activity. Predicted to be involved in protein lipoylation. Predicted to be active in mitochondrion. Orthologous to human LIPT2 (lipoyl(octanoyl) transferase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Encephalopathy, neonatal severe, with lactic acidosis and brain abnormalities | 617668 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020605 | Octanoyltransferase, conserved site |
| Domain | IPR004143 | Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain |
| Family | IPR000544 | Octanoyltransferase |
| Homologous_superfamily | IPR045864 | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) |
Domain Details Per Protein
| Protein | Additional Resources | Length | Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) | Octanoyltransferase | Octanoyltransferase, conserved site |
|---|---|---|---|---|---|---|
| UniProtKB:F1QAW5 | InterPro | 224 | ||||
| UniProtKB:Q29R99 | InterPro | 224 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers