ZFIN is now using GRCz12tu for Genomic Data
Gene
casp6b.2
- ID
- ZDB-GENE-060312-12
- Name
- caspase 6b.2, apoptosis-related cysteine peptidase
- Symbol
- casp6b.2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in apoptotic process and positive regulation of neuron apoptotic process. Predicted to act upstream of or within proteolysis. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in ovarian carcinoma. Orthologous to human CASP6 (caspase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Spead et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016129 | Peptidase family C14A, His active site |
| Domain | IPR001309 | Peptidase C14, p20 domain |
| Domain | IPR002138 | Peptidase C14, caspase non-catalytic subunit p10 |
| Domain | IPR011600 | Peptidase C14, caspase domain |
| Domain | IPR015917 | Peptidase C14A, caspase catalytic domain |
| Family | IPR002398 | Peptidase C14 family |
| Homologous_superfamily | IPR029030 | Caspase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Caspase-like domain superfamily | Peptidase C14A, caspase catalytic domain | Peptidase C14, caspase domain | Peptidase C14, caspase non-catalytic subunit p10 | Peptidase C14 family | Peptidase C14, p20 domain | Peptidase family C14A, His active site |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q29R92 | InterPro | 245 | |||||||
| UniProtKB:A0A8M6Z4Y1 | InterPro | 265 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
casp6l2-201
(1)
|
Ensembl | 1,342 nt | ||
| mRNA |
casp6l2-202
(1)
|
Ensembl | 770 nt | ||
| ncRNA |
casp6l2-002
(1)
|
Ensembl | 527 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers