ZFIN ID: ZDB-GENE-060307-2
Gene Name: BCL2 associated athanogene 6, like
Gene Symbol: bag6l    Nomenclature History

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Previous Names: bat3l, zgc:153389

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have polyubiquitin modification-dependent protein binding activity; proteasome binding activity; and ribosome binding activity. Predicted to be involved in several processes, including ERAD pathway; animal organ development; and intrinsic apoptotic signaling pathway. Predicted to localize to the BAT3 complex and nucleus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human BAG6 (BAG cochaperone 6).
Genome Resources: Alliance (1),  Gene:751663 (1),  Ensembl(GRCz11):ENSDARG00000077531 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30712 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32248 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH bag6l HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bag6l VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process brain development (more)
    Cellular Component BAT3 complex (more)
    Molecular Function polyubiquitin modification-dependent protein binding (more)
    GO Terms (all 25)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000626 Ubiquitin-like domain
    Domain IPR021925 Large proline-rich protein BAG6
    Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bag6l-202 (1)    Ensembl 3483
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bag6l No data available
    MARKER RELATIONSHIPS
    bag6l Contained in: [BAC] CH211-215A10 (1)
    bag6l Encodes: [cDNA] MGC:153389 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045380 (1) 1106 bp
    Genomic GenBank:BX510301 (1) 209585 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8Q653 (1) 1216 aa
    Sequence Information (all 29)
    ORTHOLOGY for bag6l ( Chr: 19 )
    CITATIONS (17)