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Gene

lman1

ID
ZDB-GENE-060201-4
Name
lectin, mannose-binding, 1
Symbol
lman1 Nomenclature History
Previous Names
  • fc54c09
  • fi36e01
  • wu:fc54c09
  • wu:fi36e01
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable mannose binding activity. Acts upstream of or within cellular response to estrogen stimulus. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in several structures, including axis; hatching gland; head; immature eye; and optic primordium. Human ortholog(s) of this gene implicated in factor V deficiency and factor XIII deficiency. Orthologous to human LMAN1 (lectin, mannose binding 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
22 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lman1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Combined factor V and VIII deficiency 227300
Associated With lman1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005052 Legume-like lectin
Family IPR033085 Protein ERGIC-53
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily Legume-like lectin Protein ERGIC-53
UniProtKB:Q58EK8 497
UniProtKB:F1R429 513
UniProtKB:F1QWL4 100
UniProtKB:A0A2R8Q848 577
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations