Gene
slc7a7
- ID
- ZDB-GENE-051127-5
- Name
- solute carrier family 7 member 7
- Symbol
- slc7a7 Nomenclature History
- Previous Names
-
- unm t30713
- unm_t30713
- zgc:123300
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable L-amino acid transmembrane transporter activity and basic amino acid transmembrane transporter activity. Acts upstream of or within microglia development. Predicted to be located in membrane. Is expressed in brain; myeloid cell; and pancreatic D cell. Used to study lysinuric protein intolerance. Human ortholog(s) of this gene implicated in lysinuric protein intolerance. Orthologous to human SLC7A7 (solute carrier family 7 member 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| lysinuric protein intolerance | Alliance | Lysinuric protein intolerance | 222700 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| lysinuric protein intolerance | slc7a7t30713/t30713 | standard conditions | Rossi et al., 2015 |
| lysinuric protein intolerance | WT + MO1-slc7a7 | standard conditions | Rossi et al., 2015 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Amino acid/polyamine transporter I | Cellular Amino Acid Transporter |
|---|---|---|---|
|
UniProtKB:Q2YDQ4
|
501 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc7a7-201
(1)
|
Ensembl | 2,395 nt |
Interactions and Pathways
No data available
Plasmids
No data available