Gene
zgc:123258
- ID
- ZDB-GENE-051120-84
- Name
- zgc:123258
- Symbol
- zgc:123258 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in membrane protein proteolysis. Predicted to be located in several cellular components, including endomembrane system; intracellular membrane-bounded organelle; and organelle membrane. Predicted to be active in bounding membrane of organelle and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in immunodeficiency 86. Orthologous to human SPPL2A (signal peptide peptidase like 2A).
- Genome Resources
-
- Alliance (1)
- Gene:641502 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) Single Cell Expression Atlas (1) Daniocell (1)
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | PA domain | Peptidase A22B, signal peptide peptidase | Presenilin/signal peptide peptidase |
|---|---|---|---|---|---|
| UniProtKB:Q32LU5 | InterPro | 519 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance