header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-051113-88
Gene Name: transcription factor 21
Gene Symbol: tcf21    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: capsulin (1), MyoRa2 (1), zgc:123313

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have E-box binding activity and protein dimerization activity. Involved in artery development and branchiomeric skeletal muscle development. Localizes to the nucleus. Is expressed in several structures, including mesenchymal cell; mesoderm; pericardial region; pharyngeal arch; and proepicardial cluster. Orthologous to human TCF21 (transcription factor 21).
Genome Resources: Alliance (1),  Gene:558148 (1),  Ensembl(GRCz11):ENSDARG00000036869 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sk1 Small Deletion Exon 1 Frameshift TALEN
tpl118Tg Transgenic Insertion Unknown Unknown DNA_AND_CRISPR
tpl119 Unknown Unknown Unknown CRISPR
tpl120 Unknown Unknown Unknown CRISPR
tpl144Tg Transgenic Insertion Unknown Unknown DNA_AND_CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-tcf21 1
CRISPR2-tcf21 1
CRISPR3-tcf21
1
MO1-tcf21 N/A 1
MO2-tcf21 N/A 1
TALEN1-tcf21
1
TALEN2-tcf21 1
DISEASE ASSOCIATED WITH tcf21 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH tcf21 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process artery development (more)
Cellular Component nucleus (more)
Molecular Function E-box binding (more)
GO Terms (all 27)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598 (1)
  • InterPro:IPR036638 (1)
  • PROSITE:PS50888 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tcf21-201 (1)    Ensembl 1063
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-tcf21 polyclonal IgG Rabbit WB 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tcf21
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(tcf21:GAL4-VP16-Bmo.Ecr,UAS:EGFP) tcf21 EGFPGAL4VP16 Bombyx moriDanio rerio 1 3
    tg(tcf21:gfp) tcf21 GFP Danio rerio 1 1
    Tg(tcf21:h2az2a-EGFP) tcf21 EGFPh2az2a Danio rerio 1 2
    Tg(tcf21:h2az2a-mCherry) tcf21 h2az2amCherry Danio rerio 1 2
    Tg(tcf21:LIFEACT-EGFP) tcf21 EGFPLIFEACT Danio rerio 1 2
    Tg(tcf21:mAGFP-gmnn) tcf21 gmnnmAGFP Danio rerio 1 3
    Tg(tcf21:mKOFP2-cdt1) tcf21 cdt1mKOFP2 Danio rerio 1 3
    TgBAC(cryaa:EGFP,tcf21:Cre-ERT2) cryaatcf21 CreEGFPERT2 Danio rerio 1 8
    TgBAC(tcf21:DsRed2) tcf21 DsRed2 Danio rerio 1 23
    TgBAC(tcf21:mCherry-NTR) tcf21 mCherryNTR Danio rerio 1 9
    TgBAC(tcf21:NLS-EGFP) tcf21 EGFP Danio rerio 1 17
    MARKER RELATIONSHIPS
    tcf21 Contained in: [BAC] DKEYP-79F12 (1)
    tcf21 Encodes: [cDNA] MGC:123313 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001037681 (1) 1085 bp
    Genomic GenBank:CR759830 (1) 196033 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8QQV0 (1) 176 aa
    Sequence Clusters UniGene:91652 (1)
    Sequence Information (all 15)
    ORTHOLOGY for tcf21 ( Chr: 23 )
    CITATIONS (43)