Gene

tcf21

ID

ZDB-GENE-051113-88

Name

transcription factor 21

Symbol

tcf21 Nomenclature History

Previous Names

capsulin (1)
MyoRa2 (1)
zgc:123313

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have E-box binding activity and protein dimerization activity. Involved in artery development and branchiomeric skeletal muscle development. Localizes to nucleus. Is expressed in several structures, including mesenchymal cell; mesoderm; pericardial region; pharyngeal arch; and proepicardial cluster. Orthologous to human TCF21 (transcription factor 21).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

37 figures from 20 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tcf21 Human Ortholog

No data available

Associated With tcf21 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Family	IPR050283	E-box Binding Transcriptional Regulators
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily