Gene
ppp1r7
- ID
- ZDB-GENE-051113-288
- Name
- protein phosphatase 1, regulatory (inhibitor) subunit 7
- Symbol
- ppp1r7 Nomenclature History
- Previous Names
-
- im:7136431
- zgc:123325
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including gut; heart; nervous system; otic vesicle; and pectoral fin. Orthologous to human PPP1R7 (protein phosphatase 1 regulatory subunit 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7136431 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa39803 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003603 | U2A'/phosphoprotein 32 family A, C-terminal |
| Family | IPR050576 | Ciliary and flagellar integrity-associated protein |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
| Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Ciliary and flagellar integrity-associated protein | Leucine-rich repeat | Leucine rich repeat 4 | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype | U2A'/phosphoprotein 32 family A, C-terminal |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1P634 | InterPro | 194 | ||||||
| UniProtKB:Q32PL1 | InterPro | 345 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppp1r7-201
(1)
|
Ensembl | 2,287 nt | ||
| mRNA |
ppp1r7-202
(1)
|
Ensembl | 697 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-260P23 | ZFIN Curated Data | |
| Encodes | EST | fq34g12 | Rauch et al., 2003 | |
| Encodes | EST | IMAGE:7136431 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:123325 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001037386 (1) | 2298 nt | ||
| Genomic | GenBank:CU929296 (1) | 46570 nt | ||
| Polypeptide | UniProtKB:Q32PL1 (1) | 345 aa |
No data available
- Shu, T., Shu, Y., Gao, Y., Jin, X., He, J., Zhai, G., Yin, Z. (2018) Depletion of Tissue-Specific Ion Transporters Causes Differential Expression of PRL Targets in Response to Increased Levels of Endogenous PRL. Frontiers in endocrinology. 9:683
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Wang, Y.F., Yan, J.J., Tseng, Y.C., Chen, R.D., Hwang, P.P. (2015) Molecular Physiology of an Extra-renal Cl(-) Uptake Mechanism for Body Fluid Cl(-) Homeostasis. International journal of biological sciences. 11:1190-203
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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