Gene
naga
- ID
- ZDB-GENE-051113-256
- Name
- N-acetylgalactosaminidase, alpha
- Symbol
- naga Nomenclature History
- Previous Names
-
- zgc:123333
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have alpha-galactosidase activity. Predicted to be involved in glycoside catabolic process; glycosylceramide catabolic process; and oligosaccharide metabolic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in angiokeratoma and neuroaxonal dystrophy. Orthologous to human NAGA (alpha-N-acetylgalactosaminidase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Kanzaki disease | Alliance | Kanzaki disease | 609242 |
| Schindler disease type 1 | Alliance | Schindler disease, type I | 609241 |
| Schindler disease type 1 | Alliance | Schindler disease, type III | 609241 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000111 | Glycoside hydrolase family 27/36, conserved site |
| Domain | IPR035373 | Alpha galactosidase A, C-terminal beta-sandwich domain |
| Family | IPR002241 | Glycoside hydrolase, family 27 |
| Homologous_superfamily | IPR013780 | Glycosyl hydrolase, all-beta |
| Homologous_superfamily | IPR013785 | Aldolase-type TIM barrel |
| Homologous_superfamily | IPR017853 | Glycoside hydrolase superfamily |
Domain Details Per Protein
| Protein | Length | Aldolase-type TIM barrel | Alpha galactosidase A, C-terminal beta-sandwich domain | Glycoside hydrolase, family 27 | Glycoside hydrolase family 27/36, conserved site | Glycoside hydrolase superfamily | Glycosyl hydrolase, all-beta |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IJL2
|
437 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available