Gene
primpol
- ID
- ZDB-GENE-051113-100
- Name
- primase and polymerase (DNA-directed)
- Symbol
- primpol Nomenclature History
- Previous Names
-
- zgc:123274
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable chromatin binding activity; nucleotidyltransferase activity; and transition metal ion binding activity. Predicted to be involved in DNA metabolic process; R-loop processing; and response to UV. Predicted to act upstream of or within DNA repair. Predicted to be located in replication fork. Predicted to be part of DNA-directed RNA polymerase complex. Predicted to be active in mitochondrial matrix and nucleus. Human ortholog(s) of this gene implicated in myopia. Orthologous to human PRIMPOL (primase and DNA directed polymerase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR044917 | DNA-directed primase/polymerase protein |
Domain Details Per Protein
| Protein | Length | DNA-directed primase/polymerase protein |
|---|---|---|
|
UniProtKB:Q32PL8
|
523 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
primpol-202
(1)
|
Ensembl | 614 nt | ||
| mRNA |
primpol-201
(1)
|
Ensembl | 1,960 nt | ||
| mRNA |
primpol-203
(1)
|
Ensembl | 851 nt |
Interactions and Pathways
No data available
Plasmids
No data available