Gene

slc4a2a

ID

ZDB-GENE-051101-2

Name

solute carrier family 4 member 2a

Symbol

slc4a2a Nomenclature History

Previous Names

ae2
slc4a2
ae2.1 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Exhibits anion:anion antiporter activity. Involved in anion transport. Localizes to apical plasma membrane and basolateral plasma membrane. Is expressed in several structures, including cardiovascular system; immature eye; midbrain neural rod; optic tectum; and pronephric duct. Orthologous to human SLC4A2 (solute carrier family 4 member 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

22 figures from 12 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu780 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc4a2a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Osteopetrosis, autosomal recessive 9	620366

Associated With slc4a2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018241	Anion exchange, conserved site
Domain	IPR011531	Bicarbonate transporter-like, transmembrane domain
Domain	IPR013769	Band 3 cytoplasmic domain
Family	IPR001717	Anion exchange protein
Family	IPR003020	Bicarbonate transporter, eukaryotic
Homologous_superfamily	IPR016152	Phosphotransferase/anion transporter