Gene
gamt
- ID
- ZDB-GENE-051030-97
- Name
- guanidinoacetate N-methyltransferase
- Symbol
- gamt Nomenclature History
- Previous Names
-
- zgc:123136
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable guanidinoacetate N-methyltransferase activity. Predicted to be involved in creatine biosynthetic process. Predicted to act upstream of or within methylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including digestive system; eye; heart; pleuroperitoneal region; and yolk. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and guanidinoacetate methyltransferase deficiency. Orthologous to human GAMT (guanidinoacetate N-methyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
guanidinoacetate methyltransferase deficiency | Alliance | Cerebral creatine deficiency syndrome 2 | 612736 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Arginine N-methyltransferase 2-like domain | Guanidinoacetate N-methyltransferase | RMT2/GAMT Methyltransferase | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
---|---|---|---|---|---|
UniProtKB:Q71N41
|
234 | ||||
UniProtKB:A8E5I0
|
234 |
Interactions and Pathways
No data available
Plasmids
No data available