Gene
znf622
- ID
- ZDB-GENE-050927-1
- Name
- zinc finger protein 622
- Symbol
- znf622 Nomenclature History
- Previous Names
-
- znf622l
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in cytoplasm. Predicted to be part of preribosome, large subunit precursor. Is expressed in optic cup and optic tectum. Orthologous to human ZNF622 (zinc finger protein 622).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Armant et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003604 | Matrin/U1-C-like, C2H2-type zinc finger |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Domain | IPR022755 | Zinc finger, double-stranded RNA binding |
| Domain | IPR041661 | ZN622/Rei1/Reh1, zinc finger C2H2-type |
| Family | IPR040025 | Zinc finger protein 622/Rei1/Reh1 |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Matrin/U1-C-like, C2H2-type zinc finger | Zinc finger C2H2 superfamily | Zinc finger C2H2-type | Zinc finger, double-stranded RNA binding | Zinc finger protein 622/Rei1/Reh1 | ZN622/Rei1/Reh1, zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QU59 | InterPro | 453 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
znf622-201
(1)
|
Ensembl | 2,098 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-62C1 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:6795513 | Woods et al., 2005 | |
| Has Artifact | EST | fb64b07 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_017352038 (1) | 2098 nt | ||
| Genomic | GenBank:CT476817 (1) | 173555 nt | ||
| Polypeptide | UniProtKB:F1QU59 (1) | 453 aa |
| Species | Symbol | Chromosome | Accession # | Evidence |
|---|---|---|---|---|
| Human | ZNF622 | 5 | Amino acid sequence comparison (1) |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Armant, O., März, M., Schmidt, R., Ferg, M., Diotel, N., Ertzer, R., Bryne, J.C., Yang, L., Baader, I., Reischl, M., Legradi, J., Mikut, R., Stemple, D., Ijcken, W.V., van der Sloot, A., Lenhard, B., Strähle, U., and Rastegar, S. (2013) Genome-wide, whole mount in situ analysis of transcriptional regulators in zebrafish embryos. Developmental Biology. 380(2):351-62
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
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