Gene

sagb

ID
ZDB-GENE-050913-98
Name
S-antigen; retina and pineal gland (arrestin) b
Symbol
sagb Nomenclature History
Previous Names
  • sag
  • Arrestin Sb (1)
  • zgc:114197
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled receptor binding activity. Predicted to be involved in G protein-coupled receptor internalization. Predicted to act upstream of or within signal transduction. Predicted to be active in photoreceptor inner segment and photoreceptor outer segment. Is expressed in epiphysis; eye; photoreceptor cell; retina; and retinal outer nuclear layer. Human ortholog(s) of this gene implicated in Oguchi disease-1; hereditary night blindness; and retinitis pigmentosa 47. Orthologous to human SAG (S-antigen visual arrestin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sagb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Oguchi disease-1 Alliance Oguchi disease-1 258100
retinitis pigmentosa 47 Alliance Retinitis pigmentosa 47 613758
Associated With sagb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017864 Arrestin, conserved site
Domain IPR011021 Arrestin-like, N-terminal
Domain IPR011022 Arrestin C-terminal-like domain
Family IPR000698 Arrestin
Homologous_superfamily IPR014752 Arrestin, C-terminal
Homologous_superfamily IPR014753 Arrestin, N-terminal
Homologous_superfamily IPR014756 Immunoglobulin E-set
Domain Details Per Protein
Protein Length Arrestin Arrestin, conserved site Arrestin, C-terminal Arrestin C-terminal-like domain Arrestin-like, N-terminal Arrestin, N-terminal Immunoglobulin E-set
UniProtKB:F8W5W2 208
UniProtKB:F8W374 59
UniProtKB:A0A0R4ISJ7 385
UniProtKB:F1QZZ4 176
UniProtKB:F8W470 347
UniProtKB:Q4V8R0 176
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-sag monoclonal Mouse
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations