Gene

barhl2

ID
ZDB-GENE-050913-153
Name
BarH-like homeobox 2
Symbol
barhl2 Nomenclature History
Previous Names
  • wu:fq39g04
  • zgc:113948
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including nervous system development; regulation of transcription by RNA polymerase II; and tissue development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Is expressed in alar plate midbrain region; nervous system; neural keel; and neural plate. Orthologous to human BARHL2 (BarH like homeobox 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
32 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With barhl2 Human Ortholog
No data available
Associated With barhl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR020479 Homeodomain, metazoa
Family IPR052145 Mediator complex and homeobox domain-containing protein
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeodomain Homeodomain, metazoa Mediator complex and homeobox domain-containing protein
UniProtKB:Q6YI96 364
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA barhl2-202 (1) Ensembl 1,711 nt
ncRNA barhl2-002 (1) Ensembl 766 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations