Gene
il10rb
- ID
- ZDB-GENE-050909-1
- Name
- interleukin 10 receptor, beta
- Symbol
- il10rb Nomenclature History
- Previous Names
-
- IL10R2 (1)
- il10rbl
- crfb5
- zgc:153823
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Exhibits interferon receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in head and heart. Human ortholog(s) of this gene implicated in hepatitis B; hepatitis C; and inflammatory bowel disease 25. Orthologous to several human genes including IFNAR1 (interferon alpha and beta receptor subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Levraud et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Phenotype Annotation (1994-2006)
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| inflammatory bowel disease 25 | Alliance | Inflammatory bowel disease 25, early onset, autosomal recessive | 612567 |
| {Hepatitis B virus, susceptibility to} | 610424 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Interferon/interleukin receptor domain |
|---|---|---|---|---|---|
|
UniProtKB:B8JMJ8
|
176 | ||||
|
UniProtKB:A5PF68
|
368 | ||||
|
UniProtKB:F1QA77
|
367 | ||||
|
UniProtKB:Q3HSD4
|
368 | ||||
|
UniProtKB:A0AUQ9
|
366 | ||||
|
UniProtKB:A0FJI0
|
368 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
il10rb-201
(1)
|
594 nt |
Interactions and Pathways
No data available
Plasmids
No data available