Gene

ndufa12

ID
ZDB-GENE-050828-1
Name
NADH:ubiquinone oxidoreductase subunit A12
Symbol
ndufa12 Nomenclature History
Previous Names
  • si:dkey-183c16.3 (1)
  • zgc:112053 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in response to oxidative stress. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 23. Orthologous to human NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa26308Allele with one point mutationUnknownPremature StopENU
1 - 1 of 1
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Sequence Targeting Reagents
No data available
Human Disease
Associated With ndufa12 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nuclear type mitochondrial complex I deficiency 23 Alliance Mitochondrial complex I deficiency, nuclear type 23 618244
1 - 1 of 1
Associated With ndufa12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR007763 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
1 - 1 of 1
Domain Details Per Protein
Protein Length NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
UniProtKB:Q498W6 146
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 4
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ndufa12-201 (1) Ensembl 494 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-183C16ZFIN Curated Data
EncodescDNAMGC:112053ZFIN Curated Data
1 - 2 of 2
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanNDUFA1212
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseNdufa1210
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 2 of 2
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