Gene

angptl2b

ID
ZDB-GENE-050624-1
Name
angiopoietin-like 2b
Symbol
angptl2b Nomenclature History
Previous Names
  • angptl2
  • wu:fc41g02
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to enable signaling receptor binding activity. Acts upstream of or within angiogenesis; hemopoiesis; and positive regulation of Notch signaling pathway. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including fin; gill; liver; spleen; and yolk. Orthologous to human ANGPTL2 (angiopoietin like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la029474TgTransgenic insertionUnknownUnknownDNA
sa9722Allele with one point mutationUnknownPremature StopENU
sa34443Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-angptl2bN/A (2)
MO2-angptl2bN/ALin et al., 2015
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Human Disease
Associated With angptl2b Human Ortholog
No data available
Associated With angptl2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020837 Fibrinogen, conserved site
Domain IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
Family IPR050373 Fibrinogen C-terminal domain-containing protein
Homologous_superfamily IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
Homologous_superfamily IPR036056 Fibrinogen-like, C-terminal
1 - 5 of 5
Domain Details Per Protein
Protein Length Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 Fibrinogen, conserved site Fibrinogen C-terminal domain-containing protein Fibrinogen-like, C-terminal
UniProtKB:Q5KQT9 510
UniProtKB:B0UXH5 519
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 8
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA angptl2b-201 (1) Ensembl 3,472 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(hsp70l:angptl2b)
  • angptl2b
  • Danio rerio
1 (2)
1 - 1 of 1
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Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-281H24ZFIN Curated Data
EncodesESTfc41g02
EncodescDNAMGC:194321ZFIN Curated Data
EncodescDNAMGC:194334ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanANGPTL29
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseAngptl22
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 10 of 11
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