ZFIN is now using GRCz12tu for Genomic Data
        
        
        Gene
cyp3a65
- ID
- ZDB-GENE-050604-1
- Name
- cytochrome P450, family 3, subfamily A, polypeptide 65
- Symbol
- cyp3a65 Nomenclature History
- Previous Names
- 
    
        
    
    
        
        - zgc:123110
 
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable steroid hydroxylase activity. Acts upstream of or within response to xenobiotic stimulus. Predicted to be located in membrane. Is expressed in several structures, including digestive system; eye; gill; heart; and ovary. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).
- Genome Resources
- Note
- None
- Comparative Information
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- All Expression Data
- 34 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
                
                    
                        Wild Type Expression Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    - All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
                
                    
                        Phenotype Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Mutations
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Human Disease
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Domain, Family, and Site Summary
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    
    
    
            
        
    
    
    
                
                    
                        Domain Details Per Protein
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Protein | Additional Resources | Length | Cytochrome P450 | Cytochrome P450 3A | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily | 
|---|---|---|---|---|---|---|---|
| UniProtKB:Q32LT1 | InterPro | 517 | |||||
| UniProtKB:A0A8M1N818 | InterPro | 517 | 
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis | 
|---|---|---|---|---|---|
| mRNA | cyp3a65-201
                             (1) | Ensembl | 2,020 nt | 
                
                    
                        Interactions and Pathways
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    
                
                    
                        Plasmids
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    - Genome Browsers
