Gene

hs6st1a

ID
ZDB-GENE-050524-1
Name
heparan sulfate 6-O-sulfotransferase 1a
Symbol
hs6st1a Nomenclature History
Previous Names
  • 6-ost-1a (1)
  • hs6st1 (1)
  • zgc:110038
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Enables heparan sulfate 6-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification. Predicted to be located in membrane. Is expressed in several structures, including immature eye; nervous system; neural keel; neural tube; and polster. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 15 with or without anosmia. Orthologous to human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-hs6st1aN/A (2)
MO2-hs6st1aN/A (2)
1 - 2 of 2
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Human Disease
Associated With hs6st1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 15 with or without anosmia Alliance {Hypogonadotropic hypogonadism 15 with or without anosmia} 614880
1 - 1 of 1
Associated With hs6st1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR005331 Sulfotransferase
Family IPR010635 Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
1 - 3 of 3
Domain Details Per Protein
Protein Length Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase P-loop containing nucleoside triphosphate hydrolase Sulfotransferase
UniProtKB:Q56UJ5 413
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 2
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hs6st1a-201 (1) Ensembl 737 nt
mRNA hs6st1a-202 (1) Ensembl 1,242 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEYP-82D1ZFIN Curated Data
EncodescDNAMGC:110038ZFIN Curated Data
EncodescDNAMGC:191677ZFIN Curated Data
1 - 3 of 3
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanHS6ST12
Amino acid sequence comparison (1)
MouseHs6st11
Amino acid sequence comparison (1)
Citations
1 - 4 of 4
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