Gene

derl2

ID

ZDB-GENE-050522-90

Name

derlin 2

Symbol

derl2 Nomenclature History

Previous Names

zgc:110436

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable signal recognition particle binding activity. Predicted to be involved in ERAD pathway and endoplasmic reticulum unfolded protein response. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human DERL2 (derlin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110436 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With derl2 Human Ortholog

No data available

Associated With derl2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR007599	Derlin
Homologous_superfamily	IPR035952	Rhomboid-like superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Derlin	Rhomboid-like superfamily
UniProtKB:Q4VBS8	InterPro	239

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	derl2-201 (1) Ensembl	Ensembl		4,971 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations