Gene

ets2

ID
ZDB-GENE-050522-552
Name
v-ets avian erythroblastosis virus E26 oncogene homolog 2
Symbol
ets2 Nomenclature History
Previous Names
  • wu:fe02h08
  • wu:fk74c05
  • zgc:92106
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in anterior lateral plate mesoderm; endothelial cell; head; lateral plate mesoderm; and pharyngeal arch 3-7. Orthologous to human ETS2 (ETS proto-oncogene 2, transcription factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ets2 Human Ortholog
No data available
Associated With ets2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000418 Ets domain
Domain IPR003118 Pointed domain
Domain IPR045688 Ets1, N-terminal flanking region of Ets domain
Family IPR016311 Transforming protein C-ets
Family IPR046328 ETS family
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Ets1, N-terminal flanking region of Ets domain Ets domain ETS family Pointed domain Sterile alpha motif/pointed domain superfamily Transforming protein C-ets Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q501S1 439
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ets2-202 (1) Ensembl 652 nt
mRNA ets2-203 (1) Ensembl 2,301 nt
ncRNA ets2-003 (1) Ensembl 872 nt
ncRNA ets2-004 (1) Ensembl 742 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations