Gene
ptbp1a
- ID
- ZDB-GENE-050522-492
- Name
- polypyrimidine tract binding protein 1a
- Symbol
- ptbp1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have mRNA binding activity. Involved in several processes, including intestinal epithelial structure maintenance; negative regulation of Notch signaling pathway; and positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration. Predicted to localize to nucleus. Orthologous to human PTBP1 (polypyrimidine tract binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR021790 | PTBP1-like, RNA recognition motif 2 |
| Domain | IPR035000 | PTBP1, RNA recognition motif 1 |
| Domain | IPR035001 | PTBP1, RNA recognition motif 3 |
| Family | IPR006536 | HnRNP-L/PTB |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | HnRNP-L/PTB | Nucleotide-binding alpha-beta plait domain superfamily | PTBP1-like, RNA recognition motif 2 | PTBP1, RNA recognition motif 1 | PTBP1, RNA recognition motif 3 | RNA-binding domain superfamily | RNA recognition motif domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q503D3
|
574 | |||||||
|
UniProtKB:A0A8M9QFQ9
|
573 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptbp1a-201
(1)
|
Ensembl | 3,855 nt | ||
| ncRNA |
ptbp1a-002
(1)
|
Ensembl | 541 nt |
Interactions and Pathways
No data available
Plasmids
No data available