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Gene

ptbp1a

ID
ZDB-GENE-050522-492
Name
polypyrimidine tract binding protein 1a
Symbol
ptbp1a Nomenclature History
Previous Names
  • brb
  • ptbp1
  • brom bones (1)
  • hnRNP I (1)
  • wu:fb99f12
  • zgc:110689
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable mRNA binding activity. Acts upstream of or within several processes, including intestinal epithelial structure maintenance; negative regulation of Notch signaling pathway; and positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration. Predicted to be active in nucleus. Orthologous to human PTBP1 (polypyrimidine tract binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptbp1a Human Ortholog
No data available
Associated With ptbp1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR021790 PTBP1, RNA recognition motif 2-like
Domain IPR034798 Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2
Domain IPR035000 PTBP1, RNA recognition motif 1
Domain IPR035001 PTBP1, RNA recognition motif 3
Family IPR006536 HnRNP-L/PTB
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length HnRNP-L/PTB Nucleotide-binding alpha-beta plait domain superfamily Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 PTBP1, RNA recognition motif 1 PTBP1, RNA recognition motif 2-like PTBP1, RNA recognition motif 3 RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:Q503D3 574
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations