Gene

ndufs4

ID
ZDB-GENE-050522-421
Name
NADH:ubiquinone oxidoreductase subunit S4
Symbol
ndufs4 Nomenclature History
Previous Names
  • zgc:112289
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have oxidoreductase activity, acting on NAD(P)H. Predicted to be involved in electron transport chain. Predicted to localize to mitochondrial respiratory chain complex I. Is expressed in brain; myotome; and pharyngeal arch 3-7. Human ortholog(s) of this gene implicated in Leigh disease and mitochondrial complex I deficiency. Orthologous to human NDUFS4 (NADH:ubiquinone oxidoreductase subunit S4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ndufs4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nuclear type mitochondrial complex I deficiency 1 Alliance Mitochondrial complex I deficiency, nuclear type 1 252010
Associated With ndufs4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR006885 NADH dehydrogenase ubiquinone Fe-S protein 4 mitochondrial-like
Homologous_superfamily IPR038532 NADH dehydrogenase ubiquinone Fe-S protein 4-like superfamily
Domain Details Per Protein
Protein Length NADH dehydrogenase ubiquinone Fe-S protein 4-like superfamily NADH dehydrogenase ubiquinone Fe-S protein 4 mitochondrial-like
UniProtKB:Q502E4 168
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA ndufs4-201 (1) Havana 629 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations